Structure of PDB 8sqw Chain G

Receptor sequence
>8sqwG (length=236) Species: 243233 (Methylococcus capsulatus str. Bath) [Search protein sequence]
LLDKKWLTFALAIYTVFYLWVRWYEGVYGWSAGLDSFAPEFETYWMNFLY
TEIVLEIVTASILWGYLWKTRDRNLAALTPREELRRNFTHLVWLVAYAWA
IYWGASYFTEQDGTWHQTIVRDTDFTPSHIIEFYLSYPIYIITGFAAFIY
AKTRLPFFAKGISLPYLVLVVGPFMILPNVGLNEWGHTFWFMEELFVAPL
HYGFVIFGWLALAVMGTLTQTFYSFAQGGLGQSLCE
3D structure
PDB8sqw Product analogue binding identifies the copper active site of particulate methane monooyxgenase
ChainG
Resolution2.16 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.25: methane monooxygenase (soluble).
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CU G N227 H231 H245 N183 H187 H201
BS02 HXG G W234 F235 M236 E237 P243 Y246 W190 F191 M192 E193 P199 Y202
BS03 HXG G L63 W67 Y146 Y151 L19 W23 Y102 Y107
BS04 ETF G D156 E176 N227 F240 H245 D112 E132 N183 F196 H201
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0015049 methane monooxygenase [NAD(P)H] activity
GO:0046872 metal ion binding
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8sqw, PDBe:8sqw, PDBj:8sqw
PDBsum8sqw
PubMed38187819
UniProtQ603F1

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