Structure of PDB 8qch Chain G

Receptor sequence
>8qchG (length=349) Species: 9606 (Homo sapiens) [Search protein sequence]
QQPCKTDFYSELPKVELHAHLNGSISSHTMKKLIAQKPDLKIHDQMTVID
KGKKRTLEECFQMFQTIHQLTSSPEDILMVTKDVIKEFADDGVKYLELRS
TPRRENATGMTKKTYVESILEGIKQSKQENLDIDVRYLIAVDRRGGPLVA
KETVKLAEEFFLSTEGTVLGLDLSGDPTVGQAKDFLEPLLEAKKAGLKLA
LHLSEIPNQKKETQILLDLLPDRIGHGTFLNSGEGGSLDLVDFVRQHRIP
LELCLTSNVKSQTVPSYDQHHFGFWYSIAHPSVICTDDKGVFATHLSQEY
QLAAETFNLTQSQVWDLSYESINYIFASDSTRSELRKKWNHLKPRVLHI
3D structure
PDB8qch The activation chain of the broad-spectrum antiviral bemnifosbuvir at atomic resolution
ChainG
Resolution2.442 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EIF G H26 L27 N28 F67 F70 H74 S106 T107 G181 H208 E211 D294 H20 L21 N22 F61 F64 H68 S100 T101 G175 H202 E205 D288
BS02 ZN G H24 H26 H208 D293 H18 H20 H202 D287
Gene Ontology
Molecular Function
GO:0004000 adenosine deaminase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0062154 N6-methyl-AMP deaminase activity
Biological Process
GO:0006154 adenosine catabolic process
GO:0009117 nucleotide metabolic process
GO:0046103 inosine biosynthetic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:8qch, PDBe:8qch, PDBj:8qch
PDBsum8qch
PubMed39190717
UniProtQ6DHV7|ADAL_HUMAN Adenosine deaminase-like protein (Gene Name=ADAL)

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