Structure of PDB 8h1t Chain G

Receptor sequence
>8h1tG (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
ARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLT
AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLP
NIQAVLLPK
3D structure
PDB8h1t Basis of the H2AK119 specificity of the Polycomb repressive deubiquitinase.
ChainG
Resolution3.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna G R11 K15 R17 R20 R32 R42 R2 K6 R8 R11 R23 R33
BS02 dna G R11 R29 R42 V43 G44 A45 T76 R77 R2 R20 R33 V34 G35 A36 T67 R68
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0008150 biological_process
GO:0031507 heterochromatin formation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0070062 extracellular exosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8h1t, PDBe:8h1t, PDBj:8h1t
PDBsum8h1t
PubMed36991118
UniProtP20671|H2A1D_HUMAN Histone H2A type 1-D (Gene Name=H2AC7)

[Back to BioLiP]