Structure of PDB 8guj Chain G

Receptor sequence
>8gujG (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
GKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEY
LTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGV
LPNIQAVLLPKKT
3D structure
PDB8guj Structure of the human Bre1 complex bound to the nucleosome
ChainG
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna G R11 K15 R17 R20 R32 R42 R77 R4 K8 R10 R13 R25 R35 R70
BS02 dna G R29 R42 V43 G44 A45 K75 T76 R77 R22 R35 V36 G37 A38 K68 T69 R70
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0019899 enzyme binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0008150 biological_process
GO:0031507 heterochromatin formation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:8guj, PDBe:8guj, PDBj:8guj
PDBsum8guj
PubMed38519511
UniProtP0C0S8|H2A1_HUMAN Histone H2A type 1 (Gene Name=H2AC11)

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