Structure of PDB 8dk5 Chain G

Receptor sequence
>8dk5G (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
AKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAE
ILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNI
QAVLLPK
3D structure
PDB8dk5 Structural mechanism of LIN28B nucleosome targeting by OCT4.
ChainG
Resolution2.71 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna G R29 R42 V43 G44 T76 R77 R18 R31 V32 G33 T65 R66
BS02 dna G K15 R17 R20 R32 R42 R77 K4 R6 R9 R21 R31 R66
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0008150 biological_process
GO:0031507 heterochromatin formation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Cellular Component
External links
PDB RCSB:8dk5, PDBe:8dk5, PDBj:8dk5
PDBsum8dk5
PubMed37327775
UniProtQ16777|H2A2C_HUMAN Histone H2A type 2-C (Gene Name=H2AC20)

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