Structure of PDB 8de6 Chain G

Receptor sequence
>8de6G (length=401) Species: 9606 (Homo sapiens) [Search protein sequence]
SHIDCRMSPWSEWSQCDPCLRQMFRSRSIEVFGQFNGKRCTDAVGDRRQC
VPTEPCEDAEDDCGNDFQCSTGRCIKMRLRCNGDNDCGDFSDEDDCESEP
RPPCRDRVVEESELARTAGYGINILGMDPLSTPFDNEFYNGLCNRDRDGN
TLTYYRRPWNVASLIYETKGEKNFRTEHYEEQIEASYSSKKEKMFLHVKG
EIHLGRFVMRNRDVVLTTTFVDDIKALPTTYEKGEYFAFLETYGTHYSSS
GSLGGLYELIYVLDKASMKRKVNITSENLIDDVVSLIRGGTRKYAFELKE
KLLRGTVIDVTDFVNWASSINDAPVLISQKLSPIYNLVPVKMKNAHLKKQ
NLERAIEDYINEFSVRKCHTCQNGGTVILMDGKCLCACPFKFEGIACEIS
K
3D structure
PDB8de6 The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9.
ChainG
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMA G W27 R42 W10 R25
BS02 BMA G E29 W30 E12 W13
BS03 CA G N99 D101 D103 D109 E110 N82 D84 D86 D92 E93
Gene Ontology
Biological Process
GO:0006955 immune response
Cellular Component
GO:0005579 membrane attack complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8de6, PDBe:8de6, PDBj:8de6
PDBsum8de6
PubMed36639734
UniProtP02748|CO9_HUMAN Complement component C9 (Gene Name=C9)

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