Structure of PDB 8a5v Chain G

Receptor sequence
>8a5vG (length=365) Species: 9606 (Homo sapiens) [Search protein sequence]
QVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRSSDFAKIINN
TENLVRELLAVPDNYKVIFLQGGGCGQFSAVPLNLIGLKAGRCADYVVTG
AWSAKAAEEAKKFGTINIVHPKLGSYTKIPDPSTWNLNPDASYVYYCANE
TVHGVEFDFIPDVKGAVLVCDMSSNFLSKPVDVSKFGVIFAGAQKNVGSA
GVTVVIVRDDLLGFALRECPSVLEYKVQAGNSSLYNTPPCFSIYVMGLVL
EWIKNNGGAAAMEKLSSIKSQTIYEIIDNSQGFYVCPVEPQNRSKMNIPF
RIGNAKGDDALEKRFLDKALELNMLSLKGHRSVGGIRASLYNAVTIEDVQ
KLAAFMKKFLEMHQL
3D structure
PDB8a5v L-serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase.
ChainG
Resolution2.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.6.1.52: phosphoserine transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PMP G G78 G79 C80 W107 T156 D176 S178 Q199 K200 G73 G74 C75 W102 T151 D171 S173 Q194 K195
Gene Ontology
Molecular Function
GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity
GO:0005515 protein binding
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
GO:0042802 identical protein binding
Biological Process
GO:0006563 L-serine metabolic process
GO:0006564 L-serine biosynthetic process
GO:0008615 pyridoxine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8a5v, PDBe:8a5v, PDBj:8a5v
PDBsum8a5v
PubMed36851825
UniProtQ9Y617|SERC_HUMAN Phosphoserine aminotransferase (Gene Name=PSAT1)

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