Structure of PDB 7z6h Chain G

Receptor sequence
>7z6hG (length=317) Species: 9606 (Homo sapiens) [Search protein sequence]
LPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTST
ILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGF
KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRC
TRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNI
LQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRNITEL
KTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEK
IQLSSLIAAFQVTRDLI
3D structure
PDB7z6h Structure of the human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp bound to a dsDNA-ssDNA junction.
ChainG
Resolution3.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna G G97 I98 G78 I79
BS02 AGS G V23 R27 P28 T64 T67 N156 M213 R214 V4 R8 P9 T45 T48 N137 M194 R195
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0017116 single-stranded DNA helicase activity
GO:0019899 enzyme binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0032508 DNA duplex unwinding
GO:1900264 positive regulation of DNA-directed DNA polymerase activity
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005663 DNA replication factor C complex
GO:0031390 Ctf18 RFC-like complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7z6h, PDBe:7z6h, PDBj:7z6h
PDBsum7z6h
PubMed35819203
UniProtP40937|RFC5_HUMAN Replication factor C subunit 5 (Gene Name=RFC5)

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