Structure of PDB 7yhs Chain G

Receptor sequence

>7yhsG (length=335) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]

ILSTASVLAFERKLDPSDALMSAGAWAQRDASQEWPAVTVREKSVRGTIS
NRLKTKDRDPAKLDASIQSPNLQTVDVANLPSDADTLKVRFTLRVLGGAG
TPSACNDAAYRDKLLQTVATYVNEQGFAELARRYAHNLANARFLWRNRVG
AEAVEVRINHIRQGEVARTWRFDALAIGLRDFKADAELDALAELIASGLS
GSGHVLLEVVAFARIGDGQEVFPSQELILDKGDKKGQKSKTLYSVRDAAA
IHSQKIGNALRTIDTWYPDEDGLGPIAVEPYGSVTSQGKAYRQPKQKLDF
YTLLDNWVLRDEAPAVEQQHYVIANLIRGGVFGEA

3D structure

PDB

7yhs Anti-CRISPR protein AcrIF4 inhibits the type I-F CRISPR-Cas surveillance complex by blocking nuclease recruitment and DNA cleavage.

Chain

Resolution

3.37 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	G	A32 F33 R35 V68 R69 Q248 E249 L250 H275 Q277 K278 N281 R284 G352 G353 V354	A9 F10 R12 V45 R46 Q225 E226 L227 H252 Q254 K255 N258 R261 G329 G330 V331
BS02	dna	G	S29 V30 N74 P93 N94 L95 Q96 V354 A358	S6 V7 N51 P70 N71 L72 Q73 V331 A335

External links

PDB	RCSB:7yhs, PDBe:7yhs, PDBj:7yhs
PDBsum	7yhs
PubMed	36209819

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