Structure of PDB 7tan Chain G

Receptor sequence
>7tanG (length=108) Species: 9606 (Homo sapiens) [Search protein sequence]
ARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT
AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLP
NIQAVLLP
3D structure
PDB7tan Multivalent DNA and nucleosome acidic patch interactions specify VRK1 mitotic localization and activity.
ChainG
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna G R42 V43 T76 R33 V34 T67
BS02 dna G R32 R77 R23 R68
BS03 peptide G E61 E92 E52 E83
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0019899 enzyme binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0008150 biological_process
GO:0031507 heterochromatin formation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:7tan, PDBe:7tan, PDBj:7tan
PDBsum7tan
PubMed35390161
UniProtP0C0S8|H2A1_HUMAN Histone H2A type 1 (Gene Name=H2AC11)

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