Structure of PDB 7sg1 Chain G

Receptor sequence
>7sg1G (length=179) Species: 9606 (Homo sapiens) [Search protein sequence]
SPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTL
LGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTIS
PNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVML
EMTPQRGDVYTCHVEHPSLQSPITVEWRA
3D structure
PDB7sg1 Structural basis of T cell receptor specificity and cross-reactivity of two HLA-DQ2.5-restricted gluten epitopes in celiac disease.
ChainG
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide G F11 G13 L26 Y60 W61 I67 R77 V78 N82 F9 G11 L24 Y58 W59 I65 R75 V76 N80
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7sg1, PDBe:7sg1, PDBj:7sg1
PDBsum7sg1
PubMed35065967
UniProtQ5Y7D3

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