Structure of PDB 7m5c Chain G

Receptor sequence
>7m5cG (length=139) Species: 9606 (Homo sapiens) [Search protein sequence]
SEEQVAQDTEEVFRSYVFYRHQQEPSSTMGQVGRQLAIIGDDINRRYDSE
FQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHV
YQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAAL
3D structure
PDB7m5c Structural basis of BAK activation in mitochondrial apoptosis initiation.
ChainG
Resolution3.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide G D84 I85 Y89 E92 T95 M96 H99 I114 S117 L118 N124 G126 R127 D42 I43 Y47 E50 T53 M54 H57 I72 S75 L76 N82 G84 R85
BS02 CU G H141 H145 H99 H103
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:7m5c, PDBe:7m5c, PDBj:7m5c
PDBsum7m5c
PubMed35017502
UniProtQ16611|BAK_HUMAN Bcl-2 homologous antagonist/killer (Gene Name=BAK1)

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