Structure of PDB 7jgs Chain G

Receptor sequence
>7jgsG (length=372) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
RNKYQNARRVLNSAETQNLPGRESQLQELREFFSNHLESQTSGSLYVSGQ
PGTGKTACLSLLLRDPDFSKRLQRVYINCTSIASVGAVYKKLCTELQLKV
SGRTERDHLEAIQRHLKTAKRMLLLVLDEIDQLCTSRQEVLYTIFEWPAL
PGSRILLVGIANSLDLTDRALMRLNARCELKPRLMHFPPYSKQQIVEIFK
SRLAEAEVLDVFPPVTLQLLAAKVSAISGDVRRALDIGRRVVEIAEQQKR
LKPVQVTQVAAVLNKVYFPLQQKLMLCTLVLMLRNERNKDISMGRLHEVY
RRVCAKRNILALDQAEFTGTVDLVETRGILRIMRKKEPRLHKVLLQWDEE
EVHAALSDKQLIASILSDTACL
3D structure
PDB7jgs Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
ChainG
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna G R351 R619 M621 K623 K630 R103 R331 M333 K335 K342
BS02 ATP G S261 A262 L267 P299 G300 G302 K303 T304 Y438 I446 R450 V479 R480 S13 A14 L19 P51 G52 G54 K55 T56 Y190 I198 R202 V231 R232
Gene Ontology
Molecular Function
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006270 DNA replication initiation
GO:0051301 cell division

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7jgs, PDBe:7jgs, PDBj:7jgs
PDBsum7jgs
PubMed32848132
UniProtQ9VSM9

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