Structure of PDB 7ea8 Chain G

Receptor sequence
>7ea8G (length=103) Species: 9606 (Homo sapiens) [Search protein sequence]
KTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILE
LAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAV
LLP
3D structure
PDB7ea8 Cryo-EM structure of SETD2/Set2 methyltransferase bound to a nucleosome containing oncohistone mutations.
ChainG
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna G R42 V43 R28 V29
BS02 dna G K15 R17 R20 R32 R42 K1 R3 R6 R18 R28
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
Cellular Component
GO:0000786 nucleosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:7ea8, PDBe:7ea8, PDBj:7ea8
PDBsum7ea8
PubMed33972509
UniProtP20671|H2A1D_HUMAN Histone H2A type 1-D (Gene Name=H2AC7)

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