Structure of PDB 7e2i Chain G

Receptor sequence
>7e2iG (length=151) Species: 9606 (Homo sapiens) [Search protein sequence]
LTPLAYKQFIPNVAEKTLGASGRYEGKISRNSERFKELTPNYNPDIIFKD
EENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEES
LHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAE
N
3D structure
PDB7e2i Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release.
ChainG
Resolution4.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN G H140 D147 E176 H182 H102 D109 E138 H144
Gene Ontology
Biological Process
GO:0007267 cell-cell signaling
GO:0007275 multicellular organism development
GO:0016539 intein-mediated protein splicing
GO:0016540 protein autoprocessing

View graph for
Biological Process
External links
PDB RCSB:7e2i, PDBe:7e2i, PDBj:7e2i
PDBsum7e2i
PubMed34845226
UniProtQ15465|SHH_HUMAN Sonic hedgehog protein (Gene Name=SHH)

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