Structure of PDB 7d94 Chain G

Receptor sequence
>7d94G (length=32) Species: 9823 (Sus scrofa) [Search protein sequence]
DPFYYDYETVRNGGLIFAALAFIVGLIIILSK
3D structure
PDB7d94 Binding of cardiotonic steroids to Na + ,K + -ATPase in the E2P state.
ChainG
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CLR G G29 G30 F33 G13 G14 F17
Gene Ontology
Molecular Function
GO:0001671 ATPase activator activity
GO:0005515 protein binding
GO:0030674 protein-macromolecule adaptor activity
GO:0099106 ion channel regulator activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0006883 intracellular sodium ion homeostasis
GO:0010248 establishment or maintenance of transmembrane electrochemical gradient
GO:0030007 intracellular potassium ion homeostasis
GO:0036376 sodium ion export across plasma membrane
GO:0043269 regulation of monoatomic ion transport
GO:0055085 transmembrane transport
GO:1902600 proton transmembrane transport
GO:1903408 positive regulation of P-type sodium:potassium-exchanging transporter activity
GO:1990573 potassium ion import across plasma membrane
Cellular Component
GO:0005890 sodium:potassium-exchanging ATPase complex
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:7d94, PDBe:7d94, PDBj:7d94
PDBsum7d94
PubMed33318128
UniProtQ58K79

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