Structure of PDB 6y32 Chain G

Receptor sequence
>6y32G (length=267) Species: 9606 (Homo sapiens) [Search protein sequence]
IINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDLKRKMIQHAV
FKELVKLVDPGVKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKG
WKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKF
KNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQAC
EAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHI
DDFEPFKTQPFISKLLG
3D structure
PDB6y32 Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia.
ChainG
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP G Q110 G111 G113 K114 T115 T116 R141 Q147 G193 K249 D251 G274 G276 E277 Q81 G82 G84 K85 T86 T87 R112 Q118 G164 K220 D222 G245 G247 E248
BS02 GNP G Q110 R141 Q81 R112
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0008312 7S RNA binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0048500 signal recognition particle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6y32, PDBe:6y32, PDBj:6y32
PDBsum6y32
PubMed33053321
UniProtP61011|SRP54_HUMAN Signal recognition particle subunit SRP54 (Gene Name=SRP54)

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