Structure of PDB 6w5i Chain G

Receptor sequence
>6w5iG (length=98) Species: 8355 (Xenopus laevis) [Search protein sequence]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB6w5i Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin.
ChainG
Resolution6.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna G R40 G44 V46 A47 K56 K64 L65 R69 R4 G8 V10 A11 K20 K28 L29 R33
BS02 dna G H39 R40 Y41 R42 P43 R63 R72 F84 R116 V117 T118 M120 H3 R4 Y5 R6 P7 R27 R36 F48 R80 V81 T82 M84
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6w5i, PDBe:6w5i, PDBj:6w5i
PDBsum6w5i
PubMed34012049
UniProtP84233|H32_XENLA Histone H3.2

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