Structure of PDB 6u7a Chain G

Receptor sequence
>6u7aG (length=423) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
SFDSLSPQELAALHARHQQDYAALQGMKLALDLTRGKPSAEQLDLSNQLL
SLPGDDYRDPEGTDTRNYGGQHGLPGLRAIFAELLGIAVPNLIAGNNSSL
ELMHDIVAFSMLYGGVDSPRPWIQEQDGIKFLCPVPGYDRHFAITETMGI
EMIPIPMLQDGPDVDLIEELVAVDPAIKGMWTVPVFGNPSGVTYSWETVR
RLVQMRTAAPDFRLFWDNAYAVHTLTLDFPRQVDVLGLAAKAGNPNRPYV
FASTSKITFAGGGVSFFGGSLGNIAWYLQYAGKKSIGPDKVNQLRHLRFF
GDADGVRLHMLRHQQILAPKFALVAEVLDQRLSESKIASWTEPKGGYFIS
LDVLPGTARRTVALAKDVGIAVTEAGASFPYRKDPDDKNIRIAPSFPSVP
DLRNAVDGLATCALLAATETLLN
3D structure
PDB6u7a Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis.
ChainG
Resolution2.22 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.6.1.1: aspartate transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KYA G G37 Y139 R141 F349 G36 Y138 R140 F348
BS02 PMP G S99 S100 L101 Y139 D218 A220 Y221 S254 S256 S98 S99 L100 Y138 D217 A219 Y220 S253 S255
BS03 PO4 G R59 D65 R58 D64
BS04 PO4 G E169 M206 R207 E168 M205 R206
Gene Ontology
Molecular Function
GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity
GO:0008483 transaminase activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:6u7a, PDBe:6u7a, PDBj:6u7a
PDBsum6u7a
PubMed32327655
UniProtO69689|ASPAT_MYCTU Aspartate aminotransferase (Gene Name=Rv3722c)

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