Structure of PDB 6se0 Chain G

Receptor sequence
>6se0G (length=108) Species: 9606 (Homo sapiens) [Search protein sequence]
KARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYL
TAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVL
PNIQAVLL
3D structure
PDB6se0 CENP-C unwraps the human CENP-A nucleosome through the H2A C-terminal tail.
ChainG
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna G R11 K13 R29 R42 V43 G44 A45 T76 R77 R3 K5 R21 R34 V35 G36 A37 T68 R69
BS02 dna G K15 R17 G28 R32 R77 K7 R9 G20 R24 R69
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0008150 biological_process
GO:0031507 heterochromatin formation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:6se0, PDBe:6se0, PDBj:6se0
PDBsum6se0
PubMed31475439
UniProtQ6FI13|H2A2A_HUMAN Histone H2A type 2-A (Gene Name=H2AC18)

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