Structure of PDB 6r25 Chain G

Receptor sequence
>6r25G (length=113) Species: 8355 (Xenopus laevis) [Search protein sequence]
GKTRAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEY
LTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGV
LPNIQSVLLPKKT
3D structure
PDB6r25 A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
ChainG
Resolution4.61 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna G R29 R42 V43 G44 A45 K75 T76 R77 K119 R22 R35 V36 G37 A38 K68 T69 R70 K112
BS02 dna G K15 T16 R17 R20 G28 R42 K8 T9 R10 R13 G21 R35
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:6r25, PDBe:6r25, PDBj:6r25
PDBsum6r25
PubMed30970244
UniProtP06897|H2A1_XENLA Histone H2A type 1

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