Structure of PDB 6pzv Chain G

Receptor sequence
>6pzvG (length=242) Species: 9913 (Bos taurus) [Search protein sequence]
SPKCTECLQYLDDPELRYEQHPPDAVEEIQILTNERLSIFDANESGFESY
EDLPQHKLTCFSVYCKRGHLCPIDTGLIEKDVELLFSGSAKPIYEDDPSP
EGGINGKNFGPINEWWIAGFDGGEKALLGFSTSFAEYILMDPSPEYAPLF
SVMQEKIYISKIVVEFLQSNPDSTYEDLINKIETTVPPCMLNLNRFTEDS
LLRHAQFVVEQVESYDRAGDSDEQPIFLSPCMRDLIKLAGVT
3D structure
PDB6pzv Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation.
ChainG
Resolution3.01 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide G I425 E426 D428 I459 N460 E461 W462 W463 I464 F467 E483 Q558 S561 Y562 D567 E570 I78 E79 D81 I112 N113 E114 W115 W116 I117 F120 E136 Q211 S214 Y215 D220 E223
BS02 ZN G C351 H416 C4 H69
External links
PDB RCSB:6pzv, PDBe:6pzv, PDBj:6pzv
PDBsum6pzv
PubMed32675241
UniProtQ24K09|DNMT1_BOVIN DNA (cytosine-5)-methyltransferase 1 (Gene Name=DNMT1)

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