Structure of PDB 6pwx Chain G

Receptor sequence
>6pwxG (length=98) Species: 8355 (Xenopus laevis) [Search protein sequence]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB6pwx Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
ChainG
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna G R40 Y41 P43 G44 V46 R49 R63 K64 L65 P66 R69 R4 Y5 P7 G8 V10 R13 R27 K28 L29 P30 R33
BS02 dna G Y41 R42 R63 R72 R83 F84 Q85 R116 V117 T118 M120 Y5 R6 R27 R36 R47 F48 Q49 R80 V81 T82 M84
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6pwx, PDBe:6pwx, PDBj:6pwx
PDBsum6pwx
PubMed31804488
UniProtP84233|H32_XENLA Histone H3.2

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