Structure of PDB 6pww Chain G

Receptor sequence
>6pwwG (length=98) Species: 8355 (Xenopus laevis) [Search protein sequence]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB6pww Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
ChainG
Resolution4.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna G R40 Y41 P43 G44 T45 V46 A47 R49 R63 K64 L65 P66 R69 R83 R4 Y5 P7 G8 T9 V10 A11 R13 R27 K28 L29 P30 R33 R47
BS02 dna G R42 P43 R63 R72 R83 F84 Q85 R116 V117 T118 M120 R6 P7 R27 R36 R47 F48 Q49 R80 V81 T82 M84
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:6pww, PDBe:6pww, PDBj:6pww
PDBsum6pww
PubMed31804488
UniProtP84233|H32_XENLA Histone H3.2

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