Structure of PDB 6pwv Chain G

Receptor sequence
>6pwvG (length=98) Species: 8355 (Xenopus laevis) [Search protein sequence]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB6pwv Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
ChainG
Resolution6.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna G R40 Y41 R42 P43 G44 T45 V46 A47 R49 K56 R63 K64 L65 R69 R83 R4 Y5 R6 P7 G8 T9 V10 A11 R13 K20 R27 K28 L29 R33 R47
BS02 dna G R40 Y41 R42 P43 R63 R72 F84 R116 V117 T118 M120 R4 Y5 R6 P7 R27 R36 F48 R80 V81 T82 M84
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6pwv, PDBe:6pwv, PDBj:6pwv
PDBsum6pwv
PubMed31804488
UniProtP84233|H32_XENLA Histone H3.2

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