Structure of PDB 6p8v Chain G

Receptor sequence
>6p8vG (length=320) Species: 749537 (Escherichia coli MS 115-1) [Search protein sequence]
STEHVDHKTIARFAEDKVNLPKVKADDFREQAKRLQNKLEGYLSDHPDFS
LKRMIPSGSLAKGTALRSLNDIDVAVYISGSDAPQDLRGLLDYLADRLRK
AFPNFSPDQVKPQTYSVTVSFRGSGLDVDIVPVLYSGLPDWRGHLISQED
GSFLETSIPLHLDFIKARKRAAPKHFAQVVRLAKYWARLMKQERPNFRFK
SFMIELILAKLLDNGVDFSNYPEALQAFFSYLVSTELRERIVFEDNYPAS
KIGTLSDLVQIIDPVNPVNNVARLYTQSNVDAIIDAAMDAGDAIDAAFYA
PTKQLTVTYWQKVFGSSFQG
3D structure
PDB6p8v HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity.
ChainG
Resolution2.64 Å
3D
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.85: diadenylate cyclase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP G S58 G59 S60 K63 L155 H162 K185 K201 S202 F203 N270 S57 G58 S59 K62 L154 H161 K184 K200 S201 F202 N269
Gene Ontology
Molecular Function
GO:0001730 2'-5'-oligoadenylate synthetase activity
GO:0003725 double-stranded RNA binding
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
GO:0106408 diadenylate cyclase activity
Biological Process
GO:0009117 nucleotide metabolic process
GO:0051607 defense response to virus
GO:0060700 regulation of ribonuclease activity
Cellular Component
GO:0005829 cytosol
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6p8v, PDBe:6p8v, PDBj:6p8v
PDBsum6p8v
PubMed31932165
UniProtD7Y2H2|CDNC_ECOM1 Cyclic AMP-AMP-AMP synthase (Gene Name=cdnC)

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