Structure of PDB 6p5a Chain G

Receptor sequence

>6p5aG (length=442) Species: 7227 (Drosophila melanogaster) [Search protein sequence]

ESQQLEESLRKIFTDTQIRILKNGGQRATFNSDDISTAICLHTAGPRAYN
HLYKKGFPLPSRTTLYRWLSDVDIKRGCLDVVIDLMDSDGVDDADKLCVL
AFDEMKVAAAFEYDSSADIVYEPSDYVQLAIVRGLKKSWKQPVFFDFNTR
MDPDTLNNILRKLHRKGYLVVAIVSDLGTGNQKLWTELGISESKTWFSHP
ADDHLKIFVFSDTPHLIKLVRNHYVDSGLTINGKKLTKKTIQEALHLCNK
SDLSILFKINENHINVRSLAKQKVKLATQLFSNTTASSIRRCYSLGYDIE
NATETADFFKLMNDWFDIFNSKLSTSNCIECSQPYGKQLDIQNDILNRMS
EIMRTGILDKPKRLPFQKGIIVNNASLDGLYKYLQENFSMQYILTSRLNQ
DIVEHFFGSMRSRGGQFDHPTPLQFKYRLRKYIIARNTEMLR

3D structure

PDB

6p5a Structure of a P element transposase-DNA complex reveals unusual DNA structures and GTP-DNA contacts.

Chain

Resolution

3.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.7.7.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	G	R260 S265 W266	R133 S138 W139
BS02	dna	G	K233 K263 S265 S381 F384 Q399 K400 K402 K449 L450 S451 N454 M517 Q518 Y519 R524 E531 H532 G535 R538	K106 K136 S138 S254 F257 Q272 K273 K275 K322 L323 S324 N327 M390 Q391 Y392 R397 E404 H405 G408 R411
BS03	dna	G	D303 L304 G305 H342 L346 H350	D176 L177 G178 H215 L219 H223
BS04	dna	G	R154 P173 R174 R189 Y193 S242 S243 G541 Q551 Y554 R557 K558	R27 P46 R47 R62 Y66 S115 S116 G414 Q424 Y427 R430 K431
BS05	dna	G	R154 Y180 S188 T190 T191 R194 T306 R394 S395 K489 Q543 F544	R27 Y53 S61 T63 T64 R67 T179 R267 S268 K362 Q416 F417
BS06	MG	G	D230 D303	D103 D176
BS07	GTP	G	T405 N410 D528	T278 N283 D401

External links

PDB	RCSB:6p5a, PDBe:6p5a, PDBj:6p5a
PDBsum	6p5a
PubMed	31659330
UniProt	Q7M3K2\|PELET_DROME Transposable element P transposase (Gene Name=T)

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