Structure of PDB 6n1p Chain G

Receptor sequence
>6n1pG (length=476) Species: 512566 (Streptococcus pneumoniae G54) [Search protein sequence]
LTKEMKASFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKP
HKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVDGHGNFGSM
DGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVL
PGPDFPTGALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTE
FPYMVNKTKVHEHIVRLVQEKRIEGITAVRDESNREGVRFVIEVKRDASA
NVILNNLFKMTQMQTNFGFNMLAIQNGIPKILSLRQILDAYIEHQKEVVV
RRTRFDKEKAEARAHILEGLLIALDHIDEVIRIIRASETDAEAQAELMSK
FKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIADLADILAKPER
VSQIIKDELDEVKRKFSDKRRTELMV
3D structure
PDB6n1p CryoEM structures of open dimers of Gyrase A in complex with DNA illuminate mechanism of strand passage.
ChainG
Resolution6.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna G R373 R427 R428 T430 E433 K436 R363 R417 R418 T420 E423 K426
BS02 dna G K436 S439 K426 S429
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006259 DNA metabolic process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:6n1p, PDBe:6n1p, PDBj:6n1p
PDBsum6n1p
PubMed30457554
UniProtQ8DPM2|GYRA_STRR6 DNA gyrase subunit A (Gene Name=gyrA)

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