Structure of PDB 6mu6 Chain G

Receptor sequence
>6mu6G (length=442) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
ENLWVTVYYGVPVWKDAETTLFCASDAKAKHNVWATHACVPTDPNPQEIH
LENVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVKLTPLCVTLQCTNVT
NAITDDMRGELKNCSFNMTTELRDKKQKVYSLFYRLDVVQINNKEYRLIN
CNTSAITQACPKVSFEPIPIHYCAPAGFAILKCKDKKFNGTGPCPSVSTV
QCTHGIKPVVSTQLLLNGSLAEEEVMIRSENITNNAKNILVQFNTPVQIN
CTRPNNNTRKSIRIGPGQAFYATGDIIGDIRQAHCNVSKATWNETLGKVV
KQLRKHFGNNTIIRFANSSGGDLEVTTHSFNCGGEFFYCNTSGLFNSTWI
SNGSNDSITLPCRIKQIINMWQRIGQAMYAPPIQGVIRCVSNITGLILTR
DGTETFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTRCKRR
3D structure
PDB6mu6 Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
ChainG
Resolution2.551 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 JYV G I109 W112 D113 L116 V255 S375 F376 Y384 M426 W427 Q432 M434 I74 W77 D78 L81 V210 S329 F330 Y338 M370 W371 Q376 M378
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:6mu6, PDBe:6mu6, PDBj:6mu6
PDBsum6mu6
PubMed30604750
UniProtQ2N0S6

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