Structure of PDB 6mtj Chain G

Receptor sequence
>6mtjG (length=440) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
ENLWVTVYYGVPVWKDAETTLFCASDAKHNVWATHACVPTDPNPQEIHLE
NVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVKLTPLCVTLQCTNVTNA
ITDDMRGELKNCSFNMTTELRDKKQKVYSLFYRLDVVQINNKEYRLINCN
TSAITQACPKVSFEPIPIHYCAPAGFAILKCKDKKFNGTGPCPSVSTVQC
THGIKPVVSTQLLLNGSLAEEEVMIRSENITNNAKNILVQFNTPVQINCT
RPNNNTRKSIRIGPGQAFYATGDIIGDIRQAHCNVSKATWNETLGKVVKQ
LRKHFGNNTIIRFANSSGGDLEVTTHSFNCGGEFFYCNTSGLFNSTWISN
GSNDSITLPCRIKQIINMWQRIGQAMYAPPIQGVIRCVSNITGLILTRDG
TETFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTRCKRR
3D structure
PDB6mtj Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
ChainG
Resolution2.336 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 83G G I109 W112 D113 L116 V255 S375 F376 F382 I424 N425 M426 W427 Q432 I72 W75 D76 L79 V208 S327 F328 F334 I366 N367 M368 W369 Q374
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:6mtj, PDBe:6mtj, PDBj:6mtj
PDBsum6mtj
PubMed30604750
UniProtQ2N0S6

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