Structure of PDB 6ipu Chain G

Receptor sequence
>6ipuG (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
KAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEI
LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQ
AVLLPKK
3D structure
PDB6ipu PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
ChainG
Resolution1.99 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna G R29 R35 R42 V43 G44 K75 T76 R77 R17 R23 R30 V31 G32 K63 T64 R65
BS02 dna G K13 A14 K15 R17 R32 R42 R77 K1 A2 K3 R5 R20 R30 R65
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:6ipu, PDBe:6ipu, PDBj:6ipu
PDBsum6ipu
PubMed31848352
UniProtP04908|H2A1B_HUMAN Histone H2A type 1-B/E (Gene Name=H2AC4)

[Back to BioLiP]