Structure of PDB 6i7a Chain G

Receptor sequence
>6i7aG (length=137) Species: 9606 (Homo sapiens) [Search protein sequence]
VVKFSYMWTINNFSFCREMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEE
SKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGK
DWGFKKFIRRNFLLDEANGLLPDDKLTLFCEVSVVQD
3D structure
PDB6i7a Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
ChainG
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide G Y87 Y123 K129 D130 W131 G132 F133 K134 Y58 Y94 K100 D101 W102 G103 F104 K105
External links
PDB RCSB:6i7a, PDBe:6i7a, PDBj:6i7a
PDBsum6i7a
PubMed31026449
UniProtO43791|SPOP_HUMAN Speckle-type POZ protein (Gene Name=SPOP)

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