Structure of PDB 6gjq Chain G

Receptor sequence
>6gjqG (length=187) Species: 9606 (Homo sapiens) [Search protein sequence]
DINFKIERGQLLAVAGSTGAGKTSLLMMIMGELEPSRISFCPQFSWIMPG
TIKENIIFGVSYDEYRYRSVIKACQLEEDISKFPEKDNTVLGEGGITLSG
GQRARISLARAVYKDADLYLLDSPFGYLDVLTEKEIFESCVCKLMANKTR
ILVTSKMEHLKKADKILILHEGSSYFYGTFSELQNLQ
3D structure
PDB6gjq Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
ChainG
Resolution2.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.1.6: channel-conductance-controlling ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP G D443 T460 G461 G463 K464 T465 S466 Q493 D1 T18 G19 G21 K22 T23 S24 Q43
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:6gjq, PDBe:6gjq, PDBj:6gjq
PDBsum6gjq
PubMed31201318
UniProtP13569|CFTR_HUMAN Cystic fibrosis transmembrane conductance regulator (Gene Name=CFTR)

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