Structure of PDB 6gh1 Chain G

Receptor sequence

>6gh1G (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRW

3D structure

PDB

6gh1 Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.

Chain

Resolution

2.1 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	G	Y7 H9 R62 E63 S66 N77 Y84 W97 F116 S143 K146 Y159 T163 W167 Y171	Y7 H9 R62 E63 S66 N77 Y84 W97 F116 S143 K146 Y159 T163 W167 Y171
BS02	ZN	G	H181 E183	H181 E183

External links

PDB	RCSB:6gh1, PDBe:6gh1, PDBj:6gh1
PDBsum	6gh1
PubMed	30087334
UniProt	P13747\|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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