Structure of PDB 6g63 Chain G

Receptor sequence
>6g63G (length=493) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRIE
EAAFVDYGAERHGFLPLKEIAREYFPRPNIKDVLREGQEVIVQIDKEERG
NKGAALTTFISLAGSYLVLMPNNPRAGGISRGDDRTELKEALASLGMGLI
VRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRA
FRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFS
HYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIRINSARATRGGDIEE
TAFNTNLEAADEIARQLRLRDLGGLIVIRFIDMTPVRHQRAVENRLREAV
RQDRARIQISHISRFGLLEMSRQRLSPSLGESSHHVCPRCSGTGTVRDNE
SLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIETRQD
GVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEEAM
3D structure
PDB6g63 Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E.
ChainG
Resolution3.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.12: ribonuclease E.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna G M1 R3 Q22 Y269 Q270 M1 R3 Q22 Y252 Q253
BS02 ZN G C404 C407 C387 C390
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004540 RNA nuclease activity
GO:0008995 ribonuclease E activity
Biological Process
GO:0006396 RNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:6g63, PDBe:6g63, PDBj:6g63
PDBsum6g63
PubMed30270108
UniProtP21513|RNE_ECOLI Ribonuclease E (Gene Name=rne)

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