Structure of PDB 5yj1 Chain G

Receptor sequence
>5yj1G (length=98) Species: 10090 (Mus musculus) [Search protein sequence]
GPTSLCCKQCQETEITTKNEIFSLSLCGPMHETLTVYKASNLNLIGRPST
VHSWFPGYAWTIAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLP
3D structure
PDB5yj1 Structural basis of thalidomide enantiomer binding to cereblon
ChainG
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6EL G H381 W383 W389 W403 F405 H52 W54 W60 W74 F76 MOAD: Kd=50.3uM
BS02 ZN G C326 C329 C394 C397 C7 C10 C65 C68
External links
PDB RCSB:5yj1, PDBe:5yj1, PDBj:5yj1
PDBsum5yj1
PubMed29358579
UniProtQ8C7D2|CRBN_MOUSE Protein cereblon (Gene Name=Crbn)

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