Structure of PDB 5yhw Chain G

Receptor sequence

>5yhwG (length=381) Species: 9823 (Sus scrofa) [Search protein sequence]

TVKVINDPIHGHIELHPLLIRIIDTPQFQRLRYIKQLGGGYYVFPGASHN
RFEHSLGVGYLAGCLVRELSEKQPELQISERDMLCVQIAGLCRNLGHGPF
SHMFDGRFIPLARPDVKWTHEQGSVNMFEHLVNSNGLIDVMEHYGLIPEE
DIWFIKEQITGWPYKGRPKEKSFLYEIVANKRNGIDVDKWDYFARDCHHL
GIQNNFDYKRFIKFARVCEKKHICTREKEVGNLYDMFHTRNCLHRRAYQH
KVGNIIDTMITDAFLKADPYIEITGSEGKKYRISTAIDDMEAFTKLTDNI
FLEILYSAARAILKKIECRNLYKFIVDVINMDYGMEDKNPIDNVRFYCKS
DPNKAIIITKNQVSQLLPERFAEQLIRVYCK

3D structure

PDB

5yhw Structural characterization and directed modification of Sus scrofa SAMHD1 reveal the mechanism underlying deoxynucleotide regulation.

Chain

Resolution

2.7 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	DGT	G	V156 F157 I325 R372 H376	V43 F44 I202 R246 H250
BS02	DGT	G	K116 I118 D137 R145	K3 I5 D24 R32
BS03	DGT	G	V117 N119 H125	V4 N6 H12
BS04	DGT	G	R333 R352 K354 K524	R210 R226 K228 K349
BS05	DGT	G	Q149 L150 R164 R206 H210 H215 K312 Y315 R366 H370 Y374 Q375	Q36 L37 R51 R93 H97 H102 K189 Y192 R240 H244 Y248 Q249
BS06	MG	G	R206 D309	R93 D186
BS07	DGT	G	Y155 V156 V378 R451	Y42 V43 V252 R319

External links

PDB	RCSB:5yhw, PDBe:5yhw, PDBj:5yhw
PDBsum	5yhw
PubMed	31152619
UniProt	I3LG77

[Back to BioLiP]