Structure of PDB 5vx3 Chain G

Receptor sequence
>5vx3G (length=146) Species: 9606 (Homo sapiens) [Search protein sequence]
GPLGSMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRY
RRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALC
VESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGN
3D structure
PDB5vx3 Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
ChainG
Resolution1.945 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide G F97 Y101 R103 A104 Q111 L112 Q125 V126 E129 L130 D133 N136 G138 R139 L194 Y195 F46 Y50 R52 A53 Q60 L61 Q74 V75 E78 L79 D82 N85 G87 R88 L143 Y144
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:5vx3, PDBe:5vx3, PDBj:5vx3
PDBsum5vx3
PubMed29149594
UniProtQ07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

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