Structure of PDB 5vn0 Chain G

Receptor sequence

>5vn0G (length=448) Species: 387344 (Levilactobacillus brevis ATCC 367)

SMKVTVVGCTHAGTFAIKQILAEHPDAEVTVYERNDVISFLSCGIALYLG
GKVADPQGLFYSSPEELQKLGANVQMNHNVLAIDPDQKTVTVEDLTNHAQ
TTESYDKLVMTSGSWPIVPKIPGIDSDRVKLCKNWAHAQALIEDAKEAKR
ITVIGAGYIGAELAEAYSTTGHDVTLIDAMARVMPKYFDADFTDVIEQDY
RDHGVQLALGETVESFTDSATGLTIKTDKNSYETDLAILCIGFRPNTDLL
KGKVDMAPNGAIITDDYMRSSNPDIFAAGDSAAVHYNPTHQNAYIPLATN
AVRQGILVGKNLVKPTVKYMGTQSSSGLALYDRTIVSTGLTLAAAKQQGL
NAEQVIVEDNYRPEFMPSTEPVLMSLVFDPDTHRILGGALMSKYDVSQSA
NTLSVCIQNENTIDDLAMVDMLFQPNFDRPFNYLNILAQAAQAKVAQS

3D structure

• PDB: 5vn0 A genetically encoded tool for manipulation of NADP(+)/NADPH in living cells.
• Chain: G
• Resolution: 2.001 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): H10 I37 L40 S41 C42 Q74 T101 A276 A281 A282 V301 S447
• Catalytic site (residue number reindexed from 1): H11 I38 L41 S42 C43 Q75 T102 A277 A282 A283 V302 S448

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	G	G7 T9 H10 A11 E32 R33 N34 S41 C42 V79 T110 S111 G112 K132 F242 G278 D279 L296 A297	G8 T10 H11 A12 E33 R34 N35 S42 C43 V80 T111 S112 G113 K133 F243 G279 D280 L297 A298
BS02	NAI	G	G156 Y157 I158 E161 D177 A178 K185 Y186 I240 G241 F242 P295 L296	G157 Y158 I159 E162 D178 A179 K186 Y187 I241 G242 F243 P296 L297

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0016491 oxidoreductase activity

External links

• PDB: RCSB:5vn0, PDBe:5vn0, PDBj:5vn0
• PDBsum: 5vn0
• PubMed: 28805804
• UniProt: Q03Q85