Structure of PDB 5uwc Chain G

Receptor sequence
>5uwcG (length=253) Species: 9606 (Homo sapiens) [Search protein sequence]
ITNLRMKAKAQQLTWECVKDADYSMPAVNNSYCQFGAISLCEVTNYTVRV
STWILFPENSGKPWAGAENLTCWIHDVDFLSCSWAVGPGAPADVQYDLYL
NVANRRQQYECLHYKTDAQGTRIGCRFDDISRLSSGSQSSHILVRGRSAA
FGIPCTDKFVVFSQIEILTPPQMTAKCNKTHSFMHWKMRSHFNRKFRYEL
QIQKRMQPVITEQVRDRTSFQLLNPGTYTVQIRARERVYEFLSAWSTPQR
FEC
3D structure
PDB5uwc A dual role for the N-terminal domain of the IL-3 receptor in cell signalling.
ChainG
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EDT G W113 H115 S121 R166 W73 H75 S81 R126
Gene Ontology
Molecular Function
GO:0004896 cytokine receptor activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5uwc, PDBe:5uwc, PDBj:5uwc
PDBsum5uwc
PubMed29374162
UniProtP26951|IL3RA_HUMAN Interleukin-3 receptor subunit alpha (Gene Name=IL3RA)

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