Structure of PDB 5ujt Chain G

Receptor sequence
>5ujtG (length=182) Species: 9606 (Homo sapiens) [Search protein sequence]
GEDIVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYVDLERKETVWQLP
LFRRFRRFDPQFALTNIAVLKHNLNCVIKRSNSTAATNEVPEVTVFSKSP
VTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFF
KISYLTFLPSDDEIYDCKVEHWGLDEPLLKHW
3D structure
PDB5ujt C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
ChainG
Resolution1.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide G E-1 E85 G169 D171 E2 E89 G173 D175
BS02 peptide G Y9 W43 R52 R53 F58 N62 V65 H68 N69 C72 R76 Y12 W47 R56 R57 F62 N66 V69 H72 N73 C76 R80
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5ujt, PDBe:5ujt, PDBj:5ujt
PDBsum5ujt
PubMed29255035
UniProtQ5Y7C3

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