Structure of PDB 5u7m Chain G

Receptor sequence
>5u7mG (length=442) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
AENLWVTVYYGVPVWKDAETTLFCASDAKAYKHNVWATHACVPTDPNPQE
IHLENVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVKLTPLCVTLQCTN
VTNNRGELKNCSFNMTTELRDKKQKVYSLFYRLDVVQINEYRLINCNTSA
ITQACPKVSFEPIPIHYCAPAGFAILKCKDKKFNGTGPCPSVSTVQCTHG
IKPVVSTQLLLNGSLAEEEVMIRSENITNNAKNILVQFNTPVQINCTRPN
NNTRKSIRIGPGQAFYATGDIIGDIRQAHCNVSKATWNETLGKVVKQLRK
HFGNNTIIRFANSSGGDLEVTTHSFNCGGEFFYCNTSGLFNSTWISNNDS
ITLPCRIKQIINMWQRIGQAMYAPPIQGVIRCVSNITGLILTRDGGSTNS
TTETFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTRCKRRV
3D structure
PDB5u7m Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.
ChainG
Resolution3.025 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN G S209 E211 S159 E161
BS02 83G G W112 D113 L116 S375 F376 I424 N425 M426 W427 M475 W79 D80 L83 S324 F325 I361 N362 M363 W364 M412 PDBbind-CN: -logKd/Ki=6.74,Kd=180nM
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:5u7m, PDBe:5u7m, PDBj:5u7m
PDBsum5u7m
PubMed28825711
UniProtQ2N0S5

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