Structure of PDB 5mgx Chain G

Receptor sequence
>5mgxG (length=266) Species: 9606 (Homo sapiens) [Search protein sequence]
EEWLDILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEE
PELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGRSPYIPP
HAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVLA
ANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRA
ALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNK
TIHAELSKLVKKHAAQ
3D structure
PDB5mgx The structure of FKBP38 in complex with the MEEVD tetratricopeptide binding-motif of Hsp90.
ChainG
Resolution2.18 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) L127 V137 Q138 I153 Y179 L196
Catalytic site (residue number reindexed from 1) L37 V47 Q48 I63 Y89 L106
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide G R225 N229 Y232 N277 I306 K307 F310 R311 E336 S338 N339 R135 N139 Y142 N187 I216 K217 F220 R221 E246 S248 N249
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity

View graph for
Molecular Function
External links
PDB RCSB:5mgx, PDBe:5mgx, PDBj:5mgx
PDBsum5mgx
PubMed28278223
UniProtQ14318|FKBP8_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP8 (Gene Name=FKBP8)

[Back to BioLiP]