Structure of PDB 5lzt Chain G

Receptor sequence

>5lztG (length=233) Species: 9986 (Oryctolagus cuniculus)

VVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKV
PPAINQFTQVLDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAKRP
PVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCI
LKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEI
RRHWGGNVLGPKSVARIAKLEKAKAKELATKLG

3D structure

• PDB: 5lzt Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
• Chain: G
• Resolution: 3.65 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	G	E86 R88 P89 K90 N91 I94 Q96 I98 Q99 P100 R102 L104 R106 F107 K109 P111 R112 Y113 K125 R126 L127 E158 K160 Q161 R166 R185 G192 V193 N194 T195 T198 V214 D215 P216 L219 K240 R245 R249 K250 T251 C252 T253 P297 K298 S299 R302 K305	E7 R9 P10 K11 N12 I15 Q17 I19 Q20 P21 R23 L25 R27 F28 K30 P32 R33 Y34 K46 R47 L48 E79 K81 Q82 R87 R99 G106 V107 N108 T109 T112 V128 D129 P130 L133 K154 R159 R163 K164 T165 C166 T167 P211 K212 S213 R216 K219
BS02	rna	G	T105 Y113 I114 Q117 R118 R142 H212 D213 K238 R242	T26 Y34 I35 Q38 R39 R63 H126 D127 K152 R156

Gene Ontology

Molecular Function

• GO:0003723 RNA binding

Biological Process

• GO:0000470 maturation of LSU-rRNA
• GO:0042254 ribosome biogenesis

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:5lzt, PDBe:5lzt, PDBj:5lzt
• PDBsum: 5lzt
• PubMed: 27863242
• UniProt: G1STW0|RL7A_RABIT Large ribosomal subunit protein eL8 (Gene Name=RPL7A)