Structure of PDB 5lpk Chain G

Receptor sequence
>5lpkG (length=114) Species: 9606 (Homo sapiens) [Search protein sequence]
KIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSP
MDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLS
EVFEQEIDPVMQSL
3D structure
PDB5lpk Beyond the BET Family: Targeting CBP/p300 with 4-Acyl Pyrroles.
ChainG
Resolution2.1 Å
3D
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XDM G L1073 P1074 F1075 V1079 L1084 Y1089 N1132 V1138 L27 P28 F29 V33 L38 Y43 N86 V92
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5lpk, PDBe:5lpk, PDBj:5lpk
PDBsum5lpk
PubMed28766825
UniProtQ09472|EP300_HUMAN Histone acetyltransferase p300 (Gene Name=EP300)

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