Structure of PDB 5f5f Chain G

Receptor sequence
>5f5fG (length=148) Species: 10090 (Mus musculus) [Search protein sequence]
QLSSNLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVV
QRLEPRFPQASKTSIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRTYE
ALRREHDSQIVQIAMEAGLRIAPDQWSSLLYGDQSHKSHMQSIIDKLQ
3D structure
PDB5f5f Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40.
ChainG
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna G A198 S305 G309 A21 S128 G132
BS02 rna G A299 P300 D301 K314 A122 P123 D124 K137
BS03 rna G E277 Q311 S312 K314 E100 Q134 S135 K137
BS04 rna G R219 K220 S238 K239 T240 Q247 Y250 S253 F255 K259 R42 K43 S61 K62 T63 Q70 Y73 S76 F78 K82
External links
PDB RCSB:5f5f, PDBe:5f5f, PDBj:5f5f
PDBsum5f5f
PubMed27010430
UniProtQ4VGL6|RC3H1_MOUSE Roquin-1 (Gene Name=Rc3h1)

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