Structure of PDB 5eya Chain G

Receptor sequence
>5eyaG (length=86) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHMAELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSP
YLCPQCRAVYQARPQLHKNTVLCNVVEQFLQADLAR
3D structure
PDB5eya Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway.
ChainG
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
6.3.2.n3: ISG15--protein ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN G C28 H30 C50 C53 C31 H33 C53 C56
BS02 ZN G C13 C16 C33 C36 C16 C19 C36 C39
External links
PDB RCSB:5eya, PDBe:5eya, PDBj:5eya
PDBsum5eya
PubMed27425606
UniProtQ14258|TRI25_HUMAN E3 ubiquitin/ISG15 ligase TRIM25 (Gene Name=TRIM25)

[Back to BioLiP]