Structure of PDB 5ejk Chain G

Receptor sequence
>5ejkG (length=250) Species: 11888 (Rous sarcoma virus - Prague C) [Search protein sequence]
PLREAKDLHTALHIGPRALSKASNISMQQAREVVQTCPHCPRGLGPLQIW
QTDFTLEPRMAPRSWLAVTVDTASSAIVVTQHGRVTSVAVQHHWATAIAV
MGRPKAIKTDNGSCFTSKSTREWMARWGIAHTTGAMVERANRMMKDKIRV
LAEGDGFMKRIPTSKQGEMMAKAMYALNHFERGENTKTPIQKHWRPTVLT
EGPPVKIRIETGEWEKGWNVLVWGRGYAAVKNRDTDKVIWVPSRKVKPDI
3D structure
PDB5ejk Crystal structure of the Rous sarcoma virus intasome.
ChainG
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna G R53 G245 Y246 W259 R263 R42 G226 Y227 W240 R244
BS02 ZN G H9 H13 C37 H9 H13 C37
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5ejk, PDBe:5ejk, PDBj:5ejk
PDBsum5ejk
PubMed26887497
UniProtP03354|POL_RSVP Gag-Pol polyprotein (Gene Name=gag-pol)

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