Structure of PDB 5ddy Chain G

Receptor sequence
>5ddyG (length=244) Species: 9606 (Homo sapiens) [Search protein sequence]
VPVLELFSNIWGAGTKTAQMWYQQGFRSLEDIRSQASLTTQQAIGLKHYS
DFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRRGKATCGDVDVL
ITHPDGRSHRGIFSRLLDSLRQEGFLTDDLVSQEENGQQQKYLGVCRLPG
PGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHA
LSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
3D structure
PDB5ddy Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
ChainG
Resolution3.36 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D427 D429 D490
Catalytic site (residue number reindexed from 1) D96 D98 D159
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
4.2.99.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG G G416 D427 D429 G85 D96 D98
BS02 MN G D427 D490 D96 D159
BS03 DCP G S417 R420 D427 D429 Y505 F506 N513 S86 R89 D96 D98 Y174 F175 N182
BS04 MN G S339 I341 A344 S8 I10 A13
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0034061 DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:5ddy, PDBe:5ddy, PDBj:5ddy
PDBsum5ddy
PubMed26836966
UniProtQ9UGP5|DPOLL_HUMAN DNA polymerase lambda (Gene Name=POLL)

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