Structure of PDB 5c6h Chain G

Receptor sequence
>5c6hG (length=154) Species: 9606 (Homo sapiens) [Search protein sequence]
EDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGV
QRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISF
GAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFH
VEDL
3D structure
PDB5c6h Structure of Mcl-1 complexed with Mule at 2.05 Angstroms resolution
ChainG
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide G H224 M231 K234 R248 V249 H252 V253 N260 G262 R263 T266 F318 F319 H54 M61 K64 R78 V79 H82 V83 N90 G92 R93 T96 F148 F149
BS02 peptide G Q229 R233 T280 Q59 R63 T110
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:5c6h, PDBe:5c6h, PDBj:5c6h
PDBsum5c6h
PubMed
UniProtQ07820|MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (Gene Name=MCL1)

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